- Introduction
- Where are everyone?
- The phases and challenges

Part I: The astronomical parameters NS, NP and FS
- 1st Drake: The star number of the galactic disc for stars of spectral class K, G and F
- 2nd Drake: number number per star, suitable for life in the habitable area (spectral class F, G and K)
- 3rd Drake: fraction of stable planets for 7 gy (duration of the stellar population)

Part II: The biological parameters of Drake: fl and fi
- 4th Drake: the transition from non-living to the living
- 5th Drake: the probability of intelligent life
- Macro-interval A: the crucial passage; The onset of the Eukaryotic Cell
- Macro-interval B: the second step; The birth of animals (Metazoi)
- Macro-interval B: The "solution" of the intelligence deduced by the definition of Kardasev, centered on energy by individual, and its birth within the metzoi (the Homo case)
- The oxygen curve

Part III: The social parameters of Drake: FC and FL
- 6th Drake: fraction of planets where life decides to communicate
- 7th Drake: temporal fraction lasting a civilization
- The complete Drake equation Still the paradox of Fermi (but in short, where are everyone?)
- Winners and won in the Milky Way
- Identikit of two possible intelligent alien species
- Epilogue - The mercy of the cheetah
- Appendices

Eugenio Mieli, degree in physics. He has always worked in TLC. Noting the relevance between Maccone's work in the book Mathematical Seti and the biological scenario described by Valli in the book Bacteries, Dinosaures et Kangourous: Breve Histoire de la Biodiversite, has decided to face Drake's entire equation together with the two other authors.

Andrea M.F. Valli, biophysicist and palaeontologist. He was the scientific advisor for the "Conseil general de l'Allier". Associated with the "Societe Scientifique du Bourbonnais" (Allier), he participated in the cultural dissemination with conferences on palaeontology and the evolution of life.

Claudio Maccone is a SETI astronomer, space scientist and mathematician. From 2012 to 2021, he chaired the SETI Permanent Committee of the International Academy of Astronautics (IAA), which is based in Paris. Author of over 100 scientific articles, he published 6 books about future Space Missions, SETI and Astrobiology. He is now Chair of the IAA Moon Farside Protection Permanent Committee, which aims to preserve (at the United Nations) the radio silence still existing on the other side of the moon, before it is destroyed by the political rivalries between the various countries today.